Small Lung Nodule Profile

The Small Lung Nodule Profile provides practical guidance to ensure reliable and consistent CT volume measurements of small solid lung nodules detected during lung cancer screening. By defining standardized imaging methods, performance expectations, and technical controls, this guidance helps clinicians distinguish true biological growth from measurement variability. Developed through collaboration with organizations such as Quantitative Imaging Biomarkers Alliance, Radiological Society of North America, the American Lung Association, and the Quantitative Medical Imaging Coalition, it supports confident interpretation of longitudinal CT findings in both clinical practice and research settings.

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